One of the main breakthroughs in hepatology has been the introduction of targeted therapy for viral hepatitis. Significant progress has been made, particularly in the treatment of hepatitis C: protease inhibitors (such as drugs targeting the NS3 protein) have significantly reduced viral loads, especially in patients with genotype 1. Treatment selection is increasingly based on genetic factors, like IL28B gene mutations, which improve the chances of treatment success.
In the case of hepatitis B, therapy aims not to eliminate the virus, but to suppress its activity. Modern nucleoside analogs allow for long-term control of the disease, even in patients with resistance to previous treatments.
Hepatitis E, once considered rare, is now diagnosed more frequently, including in patients who have not visited endemic regions. It is particularly dangerous for pregnant women, as it can lead to severe complications or even death. In such cases, timely access to quality medical care is especially critical.